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Year : 2017  |  Volume : 1  |  Issue : 1  |  Page : 14-18

Application of novel computing technologies regarding gait analysis, such as CatWalk XT, in spinal cord regeneration, in the fields of experimental neurosurgery and neurophysiology

Department of Physiology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland

Correspondence Address:
Wojciech Slusarczyk
Department of Physiology Medical University of Silesia ul., Medyków 18 40-752, Katowice, Ligota
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/EJSS.EJSS_3_17

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Purpose: Our project focuses on assessing the possibility of spinal cord regeneration after its injury. Trying to find an effective therapy is possible nowadays because of modern pharmacology and molecular biology achievements. Materials and Methods: The object of research is male Wistar C rats. To obtain a selective and repeatable spinal tissue damage, we use the pressure impactor. Then, rats are administered with various types of therapeutic substances, which are considered to have a neuroprotective function. Afterward, the effect of our experiment is precisely measured by CatWalk XT device which measures numerous gait parameters. Results: It was found that several parameters significantly varied between therapeutic groups, in particular, MaxContactArea, PrintLength, PrintWidth, PrintArea, SwingSpeed, and StrideLength. Conclusions: CatWalk testing is a simple yet robust tool gait analysis in rats after spinal cord injury.

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